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The core predicament of medicine - the thing that makes being a patient so wrenching, being a doctor so difficult, and being a part of society that pays the bills they run up so vexing - is uncertainty. With all that we know nowadays about people and diseases and how to diagnose and treat them, it can be hard to see this, hard to grasp how deeply uncertainty runs. As a doctor, you come to find, however, that the struggle in caring for people is more often with what you do not know than what you do. Medicine's ground state is uncertainty. And wisdom - for both the patients and doctors - is defined by how one copes with it.

The core predicament of medicine - the thing that makes being a patient so wrenching, being a doctor so difficult, and being a part of society that pays the bills they run up so vexing - is uncertainty. With all that we know nowadays about people and diseases and how to diagnose and treat them, it can be hard to see this, hard to grasp how deeply uncertainty runs. As a doctor, you come to find, however, that the struggle in caring for people is more often with what you do not know than what you do. Medicine's ground state is uncertainty. And wisdom - for both the patients and doctors - is defined by how one copes with it.

Approximate author period: c. 1965 AD · modern

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Attribution & collection notes
Author or tradition
Atul Gawande
Attribution: attributed
Country attributed
Not established
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Historical period
Approximate author period: c. 1965 AD · modern
Approximate author-period evidence for Atul Gawande: documented birth year 1965; activity date not established. Wikidata Q2751383, inspected 2026-10-08. Not a quotation composition date or independent verification of attribution. Source: https://www.wikidata.org/wiki/Q2751383 (accessed 2026-10-08).
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Supplied reference C; CSV row 370601; supplied attribution, independently unverified

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