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a typical chromosomal DNA molecule in a human being is composed of about five billion pairs of nucleotides… But since there are four different kinds of nucleotides, the number of bits of information in DNA is four times the number of nucleotide pairs. Thus if a single chromosome has five billion (5 X 10^9) nucleotides, it contains twenty billion (2 X 10^10) bits of information… We also see that if more than some tens of billions (several times 10^10) of bits of information are necessary for human survival, extragenetic systems will have to provide them: the rate of development of genetic systems is so slow that no source of such additional biological information can be sought in the DNA.

a typical chromosomal DNA molecule in a human being is composed of about five billion pairs of nucleotides… But since there are four different kinds of nucleotides, the number of bits of information in DNA is four times the number of nucleotide pairs. Thus if a single chromosome has five billion (5 X 10^9) nucleotides, it contains twenty billion (2 X 10^10) bits of information… We also see that if more than some tens of billions (several times 10^10) of bits of information are necessary for human survival, extragenetic systems will have to provide them: the rate of development of genetic systems is so slow that no source of such additional biological information can be sought in the DNA.

Approximate author period: c. 1965 AD · modern

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Attribution & collection notes
Author or tradition
Carl Sagan
Attribution: attributed
Country attributed
Not established
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Historical period
Approximate author period: c. 1965 AD · modern
Approximate author-period anchor from life dates 1934 to 1996; Wikidata Q410, https://www.wikidata.org/wiki/Q410 (accessed 2026-10-08). Not a quotation composition date.
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Supplied reference C; CSV row 101873; supplied attribution, independently unverified

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